<?xml version="1.0" encoding="ISO-8859-1"?>
<!--
/*      This program is free software; you can redistribute it and/or modify  */
/*       it under the terms of the GNU General Public License as published by */
/*       the Free Software Foundation; either version 2 of the License, or    */
/*       (at your option) any later version.                                  */

/*       This program is distributed in the hope that it will be useful, but  */
/*       WITHOUT ANY WARRANTY; without even the implied warranty of           */
/*       MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the GNU    */
/*       General Public License for more details.                             */

/*       You should have received a copy of the GNU General Public License    */
/*       along with this program; if not, write to the Free Software          */
/*       Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA  02111-1307 */
/*       USA                                                                  */

/*       Marine Dumousseau                                                    */
/*       EMBL-EBI, neurobiology computational group,                          */
/*       Cambridge, UK. e-mail: marine@ebi.ac.uk                   */
-->
<!--/******************************************************************************/ 
    contains the parameters for mRNA/RNA hybridisation of Turner et al (2006)   */
/* Nucleic acids research 34: 3609-3614                                                                   
/******************************************************************************/-->

	<data type="crick">
		<neighbor sequence="mAA/UU">
	        <enthalpy>-7480.0</enthalpy>
            <entropy>-22.3</entropy>
	   	</neighbor> 
	   	<neighbor sequence="mAC/UG">
	       	<enthalpy>-6320.0</enthalpy>
            <entropy>-15.2</entropy>
		</neighbor> 
	   	<neighbor sequence="mAG/UC">
	       	<enthalpy>-13940.0</enthalpy>
            <entropy>-39.1</entropy>
    	</neighbor> 
	    <neighbor sequence="mAU/UA">
	       	<enthalpy>-6330.0</enthalpy>
            <entropy>-17.7</entropy>
    	</neighbor>                            
        <neighbor sequence="mCA/GU">
	       	<enthalpy>-5210.0</enthalpy>
            <entropy>-10.7</entropy>
	   	</neighbor> 
	   	<neighbor sequence="mCC/GG">
	       	<enthalpy>-8880.0</enthalpy>
            <entropy>-19.7</entropy>
	   	</neighbor> 
	   	<neighbor sequence="mCG/GC">
        	<enthalpy>-9470.0</enthalpy>
            <entropy>-23.0</entropy>
	   	</neighbor> 
	    <neighbor sequence="mCU/GA">
	       	<enthalpy>-9590.0</enthalpy>
            <entropy>-23.89</entropy>
	    	</neighbor>                          
       <neighbor sequence="mGA/CU">
	        <enthalpy>-5770.0</enthalpy>
            <entropy>-11.9</entropy>
	   	</neighbor> 
	   	<neighbor sequence="mGC/CG">
	       	<enthalpy>-11900.0</enthalpy>
            <entropy>-26.3</entropy>
	   	</neighbor> 
	   	<neighbor sequence="mGG/CC">
	       	<enthalpy>-9660.0</enthalpy>
            <entropy>-22.1</entropy>
	   	</neighbor> 
	   	<neighbor sequence="mGU/CA">
	       	<enthalpy>-6620.0</enthalpy>
            <entropy>-14.3</entropy>
	   	</neighbor>                   
        <neighbor sequence="mUA/AU">
	       	<enthalpy>-6470.0</enthalpy>
            <entropy>-17.0</entropy>
    	</neighbor> 
	    <neighbor sequence="mUC/AG">
	       	<enthalpy>-9650.0</enthalpy>
            <entropy>-25.0</entropy>
    	</neighbor> 
		<neighbor sequence="mUG/AC">
	        <enthalpy>-12140.0</enthalpy>
            <entropy>-32.9</entropy>
	   	</neighbor> 
	   	<neighbor sequence="mUU/AA">
	       	<enthalpy>-5430.0</enthalpy>
            <entropy>-14.5</entropy>
        </neighbor>                 
     
     	<initiation>
            <enthalpy>-12800.0</enthalpy>
            <entropy>-52.0</entropy>
        </initiation>
        
        <terminal type="per_A/U">
            <enthalpy>3140.0</enthalpy>
            <entropy>9.1</entropy>
        </terminal> 
        
        <symmetry>
            <enthalpy>0.0</enthalpy>
            <entropy>-1.4</entropy>
        </symmetry> 
      </data>
