<?xml version="1.0" encoding="ISO-8859-1"?>
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/*       This program is distributed in the hope that it will be useful, but  */
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/*       USA                                                                  */

/*       Marine Dumousseau                                                    */
/*       EMBL-EBI, neurobiology computational group,                          */
/*       Cambridge, UK. e-mail: marine@ebi.ac.uk                   */
-->

 <!--/******************************************************************************/
    	/* contains the parameters for RNA/RNA hairpin loop of ;
	REF: Douglas M Turner et al (2006). Nucleic Acids Research 34: 4912-4924.
	REF: Douglas M Turner et al (1999). J.Mol.Biol.  288: 911_940. 
    	/******************************************************************************/-->

		<data type="hairpin_loop">
			<hairpin type="initiation" size="3">
   				<enthalpy>1300.0</enthalpy>
   				<entropy>-14.2</entropy>
   			</hairpin>
   			<hairpin type="initiation" size="4">
   				<enthalpy>4800.0</enthalpy>
   				<entropy>-2.6</entropy>
   			</hairpin>
   			<hairpin type="initiation" size="5">
   				<enthalpy>3600.0</enthalpy>
   				<entropy>-6.4</entropy>
   			</hairpin>
   			<hairpin type="initiation" size="6">
   				<enthalpy>-2900.0</enthalpy>
   				<entropy>-26.8</entropy>
   			</hairpin>
   			<hairpin type="initiation" size="7">
   				<enthalpy>1300.0</enthalpy>
   				<entropy>-14.8</entropy>
   			</hairpin>
   			<hairpin type="initiation" size="8">
   				<enthalpy>-2900.0</enthalpy>
   				<entropy>-27.4</entropy>
   			</hairpin>
   			<hairpin type="initiation" size="9">
   				<enthalpy>5000.0</enthalpy>
   				<entropy>-4.5</entropy>
   			</hairpin>
   			<hairpin type="initiation" size=">9">
   				<enthalpy>5000.0</enthalpy>
   				<entropy equation="1000/310.15x(-1.4 - 1085.5ln(n/9)"></entropy>
   			</hairpin>
   			
   			<bonus type="first_mismatch" sequence="U/U">
   				<enthalpy>-5800.0</enthalpy>
   				<entropy>-16.1</entropy>
   			</bonus>
   			<bonus type="first_mismatch" sequence="G/A_not_A/G">
   				<enthalpy>-5800.0</enthalpy>
   				<entropy>-16.1</entropy>
   			</bonus>
   			<closure type="per_G/U">
   				<enthalpy>-14800.0</enthalpy>
   				<entropy>-40.6</entropy>
   			</closure>
   			
   			<penalty type="oligo_C_loop_3">
   				<enthalpy>1860.0</enthalpy>
   				<entropy>55.5</entropy>
   			</penalty>
   			
   			<penalty type="oligo_C_loop_>3" parameter="A">
   				<enthalpy>3400.0</enthalpy>
   				<entropy>10.1</entropy>
   			</penalty>
   			<penalty type="oligo_C_loop_>3" parameter="B">
   					<enthalpy>7600.0</enthalpy>
   					<entropy>19.3</entropy>
   			</penalty>
   		</data>